Innovative multi-layer chemical barrier to provide exceptional protection to a wide range of organic and inorganic chemicals and biological agents. Features dual zipper, double cuffs, and welded and taper seams for the highest barrier to liquids and particulates. Ideal use for a variety of applications, including contaminated environments, chemical handling, filling, blending and charging of raw materials, opening and draining pumps, valves or lines, and Hazmat response. Knitted inner cuffs and inner textile type fabric provide enhanced comfort as well as superior protection.