Superior quality offers durability, temperature control, and the box adds additional preprinted handling instructions, such as Rush Perishable and This End Up for carriers and recipients. Foam container is pre-inserted in each shipping box—taking the guess work out of trying to find the correct shipping box. Typically taped on the bottom and only requires the end user to load the box with appropriate refrigerants, product, tape, and ship. Ideal for overnight (12-24 hr) shipments.